Table 1.

ACTIVATE outcome measures

Patient completed measure—primary	Description	Range
UK version of Seattle Angina Questionnaire (SAQ-UK) Physical Limitation domain15	Measures how daily activities are limited by angina over the past 4 weeks. Items are weighted equally, summed and transformed to a 0–100 score. Higher score indicates better functioning.	(0–100)
Patient completed measures—secondary
SAQ-UK Angina Frequency and Perception and Treatment Satisfaction domains15	Remaining two domains of SAQ-UK. Items are weighted equally, summed and transformed to a 0–100 score. Higher scores represent higher levels of health or satisfaction with treatment.	(0–100)
MRC dyspnoea scale16	Five item questionnaire that assesses the degree of shortness of breath with common activities. One point is assigned to each activity associated with dyspnoea. Higher scores indicates more limitation due to dyspnoea.	(0–5)
Hospital Anxiety and Depression Scale17	Measures anxiety (seven items) and depression (seven items) in patients with physical health problems. Two subscales with higher scores indicating greater anxiety or depression.	(0–21)
General Self-Efficacy scale18	Measures optimistic self-belief to cope with a variety of difficult demands in life. Higher score indicates greater self-efficacy.	(10–40)
International Physical Activity Questionnaire20	This questionnaire supplements the accelerometer data by providing self-reported duration (minutes) and frequency (days) of physical activity in the previous 7 days in the domains: job related, transportation, housework, recreation and sitting.	Minutes of light, moderate and vigorous physical activity
Patient Completed Economic Measures
EQ-5D-5L22	Health utility index with five dimensions (mobility, self-care, usual activities, pain/discomfort, anxiety/depression) and five levels to give health states converted to a utility weight. Also Visual Analogue Score (VAS) for health state today	Health utility weight from 0 (death) to 1.0 (perfect health) also with negative values VAS (0–100)
Client Service Receipt Inventory23	Collects information about health service use, including medication, smoking cessation, diet management, weight control programmes and exercise referral schemes.	According to activity
Objective measures of physical activity and function
Physical activity measured with the ActivPAL accelerometer19	The ActivPAL device is a small, slim monitor worn on the thigh. It provides accelerometer-derived information about thigh position and acceleration to determine body posture (sitting, lying or upright), stepping and stepping speed (cadence), from which energy expenditure can be inferred. It will be worn for 7 days to measure step count, energy expenditure, duration of sedentary, light, moderate and vigorous physical activity. Participants will be asked to keep a wear diary documenting working hours, sleep, removal reasons and any other comments.	Step count, energy expenditure, duration of sedentary, light, moderate and vigorous physical activity
Incremental Shuttle Walk Test21	Progressive walking test that requires the participant to walk up and down a 10 m course, at a speed dictated by an audio signal. The time between signals is reduced every minute and there are 12 levels. The test ends when the participant either (a) is too breathless to maintain the required speed or (b) fails to complete a shuttle in the time allowed or (c) reaches 85% of the predicted maximal heart rate.	Metres walked

EQ-5D-5L, EuroQol-5 Dimensions-5 Levels; MRC, Medical Research Council.