TABLE 2.
Data for transfusion of CD4+ T-cell line at days 13 (2 × 106) and 3 (1 × 106) before BDV infectiona
| T-cell transfer | Day p.i. | Symptoms | Encephalitis | Antibody titer (log2) | Virus titer (log10) | Presence of mRNA
|
||
|---|---|---|---|---|---|---|---|---|
| BDV | CD8 | Perforin | ||||||
| − | 9 | 0, 0 | 0, 0 | <1, <1 | 2.5, 3.0 | +, + | −, − | −, − |
| + | 9 | 0, 0 | 0.5, 1.0 | 1, 4 | 2.5, 3.0 | +, + | +, + | +, + |
| − | 14 | 0, 0.5 | 0.5, 1.0 | 6, ≥8 | 3.0, 5.3 | +, + | +, + | +, + |
| + | 14 | 0.5, 0.5 | 0.5, 1.0 | ≥8, ≥8 | 1.0, 3.0 | +, + | +, + | +, + |
| − | 23 | 1.5, 1.5 | 1.5, 2.0 | ≥8, ≥8 | 5.3, 5.3 | +, + | +, + | +, − |
| + | 23 | 0, 0 | 0, 0 | ≥8, ≥8 | <1.0, <1.0 | −, − | +, + | +, + |
Data are for individual rats. Encephalitis and clinical scores were on a scale ranging from 0 to 3.