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. 2024 Mar 27;29:202. doi: 10.1186/s40001-024-01804-9

Table 3.

Analysis of threshold effects

eGFR (mL/minute/1.73 m2) ACR (mg/g)
Standard linear regression model 1.08 (1.00, 1.15) 0.044 1.22(1.14, 1.30) < 0.001
Two-stage regression models
 Inflection point (K) 1.86 3.09
  < K 1.37 (1.15, 1.64) < 0.001 1.52(1.37, 1.68) < 0.001
  > K 0.99 (0.90, 1.08) 0.771 0.96(0.86, 1.07) 0.445
 log-likelihood ratio test 0.003  < 0.001

The adjustment strategy is the same as the fully adjusted regression model