Table 1.
Description of traits used in MR analyses
| Traits | Data source | Sample size | Ancestry | PubMed ID |
|---|---|---|---|---|
| Type 1 diabetes mellitus | Meta-analysis | 17,685 | European | 33830302 |
| Type 2 diabetes mellitus | DIAGRAM | 110,452 | European | 24509480 |
| Gestational diabetes mellitus | UK Biobank | 247,540 | European | 34737426 |
| Fasting insulin | Meta-analysis | 151,013 | European | 34059833 |
| Fasting glucose | MAGIC | 133,010 | European | 22885924 |
| Hemoglobin A1c | Within family GWAS consortium | 45,734 | European | 35534559 |
| Endometriosis | FinnGen | 77,257 | European | NA |
| leptin | GWAS Catalog | 56,802 | European | 32917775 |
| adiponectin | ADIPOGen | 39,883 | European | 22479202 |
| resistin | GWAS Catalog | 3,301 | European | 29875488 |
| IL-1B | GWAS Catalog | 3,301 | European | 29875488 |
| IL-6 | GWAS Catalog | 8,189 | European | 27989323 |
| IL-8 | GWAS Catalog | 21,758 | European | 33067605 |
| IL-10 | GWAS Catalog | 7,681 | European | 27989323 |
| TNF-α | GWAS Catalog | 3,454 | European | 27989323 |