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. 2024 Mar 27;24:119. doi: 10.1186/s12871-024-02494-w

Table 2.

Deviation of Vc depending on the blood hemoglobin-albumin (Hb-Alb) dilution difference. Line (A) Ranges of Hb-Alb dilution differences. Line (B)Vc as given by the covariance between the Hb-Alb dilution difference and the typical value (tv) of Vc after considering the difference in body weight between the groups. Line (C) The volume that corresponds to the deviation of the assumed albumin balance. Line (D) The size of Vc if the Hb-Alb dilution difference had been zero

Awake Anesthesia
A. Modeled difference -0.15 + 0.20 -0.15 + 0.20
B. Vc (L) 3.81 2.55 3.58 2.40
C. Volume (= A x B) -0.57 + 0.51 -0.54 + 0.48
D. Corrected Vc. (= B-C) 3.24 2.82 3.04 2.88

Based on all four subgroups, C can be estimated as 3000 * A – 105