Table 2.
Top hub proteins with the highest number of interactions
| Gene Name | Protein description | #Interacting proteins |
|---|---|---|
| Control vs. LPS | ||
| UBE2C | ubiquitin conjugating enzyme E2C | 7 |
| PBK | PDZ binding kinase | 6 |
| NOTCH2 | notch 2 | 4 |
| NUF2 | NUF2, NDC80 kinetochore complex component | 4 |
| IRS1 | insulin receptor substrate 1 | 4 |
| Control vs. PDLSC-CM | ||
| HSP90AA1 | heat shock protein 90 kDa α family, member A1 | 31 |
| RPS5 | ribosomal protein S5 | 27 |
| HRAS | Harvey rat sarcoma viral oncogene homolog | 27 |
| BYSL | bystin like | 27 |
| NOP58 | NOP58 ribonucleoprotein | 26 |
| LPS vs. LPS + PDLSC-CM | ||
| HSPA5 | heat shock protein family A (Hsp70) member 5 | 11 |
| BUB1B | BUB1 mitotic checkpoint serine /threonine kinase B | 9 |
| TPR | translocated promoter region, nuclear basket protein | 9 |
| HIST2H2AC | histone cluster 2, H2ac | 9 |
| ASPM | abnormal spindle microtubule assembly | 8 |