Table 3.
Univariate and multivariate Cox regression analyses for PFS.
| Characteristic | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| HR | 95%CI | P | HR | 95%CI | P | |
| Child–Pugh classification(B/A) | 1.153 | 0.548 ∼ 2.426 | 0.708 | |||
| No. of tumors (≥ 3/<3) | 1.291 | 0.806 ∼ 2.067 | 0.288 | |||
| Tumor diameter (≥ 5 cm/<5 cm) | 1.092 | 0.673 ∼ 1.771 | 0.723 | |||
| Portal vein tumor thrombus (yes/no) | 1.928 | 0.991 ∼ 3.751 | 0.053 | 2.103 | 1.072 ∼ 4.125 | 0.031 |
| Extrahepatic metastases(yes/no) | 1.034 | 0.633 ∼ 1.689 | 0.893 | |||
| AFP (≥ 400ng/mL/<400ng/mL) | 1.299 | 0.831 ∼ 2.032 | 0.251 | |||
| Treatment option (TACE + T/TACE + TC) | 1.605 | 1.035 ∼ 2.488 | 0.034 | 1.621 | 1.045 ∼ 2.514 | 0.031 |
| Interval of recurrence from initial treatment(<1 year/≥1 year) | 0.519 | 0.305 ∼ 0.881 | 0.015 | 0.494 | 0.289 ∼ 0.844 | 0.010 |
| MVI(Positive/Negative) | 1.298 | 0.838 ∼ 2.008 | 0.242 | |||
AFP, a-fetoprotein; MVI, microvascular invasion; No. of tumors, number of tumors.