Table 4.
H. pylori eradication rates of each regimen according to high or low MIC levels in the different patterns of resistance.
| H. pylori Susceptibility Pattern and Level of Resistance | Concomitant | Hybrid | p-Value |
|---|---|---|---|
| Dual-resistant strains (n) | 17 | 15 | |
| Dual High Resistant | 8/12 (66%) | 6/13 (46%) | 0.7 |
| MET High and CLA Low Resistant | 2/2 (100%) | 0 | NA |
| CLA High and MET Low Resistant | 1/2 (50%) | 2/2 (100%) | 0.5 |
| Dual Low Resistant | 1/1 (100%) | 0 | NA |
| CLA single-resistant strains (n) | 22 | 21 | |
| CLA High Resistant | 16/19 (86%) | 11/13 (85%) | 0.6 |
| CLA Low Resistant | 3/3 (100%) | 8/8 (100%) | NA |
| MET single-resistant strains (n) | 28 | 32 | |
| MET High Resistant | 19/20 (95%) | 22/28 (78.5%) | 0.2 |
| MET Low Resistant | 8/8 (100%) | 4/4 (100%) | NA |
NA = not applicable, MET = metronidazole, CLA = clarithromycin. High resistance has an MIC value of more than 8 to 256 mg/L for CLA and more than 32 to 256 mg/L for MET. Low resistance is more than 0.5 to 8 mg/L for CLA and more than 8 to 32 mg/L for MET.