Figure 7. Unbiased hierarchical clustering of macrophages reveals distinct RAGE-enriched subsets.

(A) CITRUS hierarchical tree with shaded groups of clusters that are differentially abundant between the experimental groups. The numbered groups (denoted as 1–3) represent clusters with RAGE enrichment. (B–E) Differential expression of representative surface markers colored based on intensity of expression are depicted in CCR2 (B), MHCII (C), RAGE (D), and TIM4 (E).