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. 2024 Mar 6;13(3):243. doi: 10.3390/antibiotics13030243

Table 3.

C. difficile PCR-positive cases.

No. Underlying
Disease
Symptoms Age Sex Time to PCR Result (h) Length of Stay in the ED (h) Hospitalization CDI Diagnosis Start of Antibiotic Treatment after Admission to the ED (h) Iso-Lation
(h)
Hospital Length of Stay (h)
PCR Ct Value WBC 1 (Gpt/mL) Creatinine 1 (mmol/L) Recurrence (R), First Diagnosis (F), or non Relevant (N)
1 Stroke condition Diarrhea and fever 74 f 4.83 11.5 No 2 26.3 24.8 88 R Vancomycin and metronidazole (7.22)
2 COPD 3, Crohn’s disease, recurrent UTI 4, and CHD 5 Diarrhea, kidney failure, and metabolic acidosis 73 m 4.25 6.77 Yes 24.7 12.6 246 F Vancomycin (5.1) and piperacillin– tazobactam (5.75) 161.75 168.5
3 Alzheimer’s disease and recurrent UTI 4 Diarrhea 96 f 3.68 10.17 Yes 25.1 22.4 113 F None 259 269.32
4 Diabetes Diarrhea 93 f 4.14 N.D. No 2 31.1 13.8 69 F Metronidazole
5 Kidney disease with dialysis and diabetes Abdominal pain, nausea, and fever 78 m 12.5 4.48 Yes 24.3 8.1 349 R None 254.5 259
6 Hirschsprung’s disease Obstipation and vomiting 1 m 4.01 <1 Yes 27.7 14.3 20 N None 47 47.15
7 Alcoholism Diarrhea for one week and cachexia 69 f 3.63 11.67 Yes 20.9 5.6 60 F Vancomycin (t.n.a. 6) 182.33 193.98
8 Rheumatoid arthritis and chronic renal failure Diarrhea for one week and exsiccosis 94 m 15.3 2.93 Yes 21.9 24.1 184 R Vancomycin (19.17) 331.25 334.17
9 Rectal carcinoma and chronic renal failure Ileus, abdominal pain, and weight loss 83 m 13.75 4.1 Yes 31.7 15.4 106 N Metronidazole (15.5) 0 7 280.25
10 Ulcerative colitis and chronic renal failure Diarrhea and fever 90 f 12.75 5.87 Yes 23.5 11.3 110 R Vancomycin, metronidazole (9.5) 204 209.82
11 Granulomatosis, monoclonal gammopathy, diabetes, dementia, UTI 4, and sepsis Diarrhea and fever 85 f 18 6.84 Yes 36.8 22.7 285 F Vancomycin (t.n.a. 6) and piperacillin–tazobactam (2) 215.5 577.23
12 CHD 5, asthma, and osteosynthesis after femur fracture Diarrhea for more than one week 85 f 19.6 5.22 Yes 28.3 15.1 132 F Vancomycin (t.n.a. 6) 143 148.25
13 Chronic venous insufficiency, recurrent UTI 4, and abscessed symphysis Diarrhea, exsiccosis, and fever 80 m 8.1 3.85 Yes 23.3 31 63 F Vancomycin (t.n.a 6) 114.5 129.78
14 Stroke condition, adipositas, sepsis Diarrhea and fever 75 f 22.6 4.25 Yes 8 22.2 21.9 80 F Vancomycin. Metronidazole (t.n.a. 6) and piperacillin–tazobactam (0.7) t.n.a. 6 t.n.a. 6
15 Malignant melanoma Diarrhea and fever 46 m 12.43 2.75 Yes 26.3 4.9 39 F Vancomycin and ampicillin–sulbactam (13.23) 417 420.03
16 Hirschsprung’s disease Diarrhea and fever <1 f 13.6 <1 Yes 23.2 18.4 N.D. F Metronidazole (14) 137.88 137.88
17 Pancreatic carcinoma Diarrhea, exsiccosis, and abdominal pain 59 m 5.38 10.37 Yes 31.6 15 60 F Vancomycin (15.25) 125.25 135.67
18 Alzheimer’s disease, CHD 5, diabetes, and chronic renal failure Diarrhea 83 f 3.07 8.17 Yes 26 4.7 168 F Vancomycin and metronidazole (6.1) 151.5 159.6
19 Hodgkin‘s disease, conditions after CDI, and sepsis Diarrhea and vomiting 60 m 5.08 8.97 Yes 28.4 21.4 103 R Vancomycin (8.75) and meropenem (4.75) 188.5 197.52
20 Short bowel syndrome, ileostomy Abdominal pain, fever 12 m 5.5 4 No 9 29.4 6 41 N None

1 Reference ranges: white blood cells (WBC) 4.5–11.3 Gpt/L and creatinine 44–80 μmol/L. 2 Nursing home. 3 COPD: chronic obstructive pulmonary disease. 4 UTI: urinary tract infection. 5 CHD: coronary heart disease. 6 t.n.a.: time not available. 7 Hygiene management error. 8 Transfer into another hospital. 9 No clinical relevance.