Dietary silybin supplementation alleviated hepatic inflammation induced by paraquat in piglets. The concentration of TNF-α (A), IL-6 (B), IL-8 (C), and IL-10 (D). The mRNA expression level of TNF-α (E), IL-6 (F), IL-8 (G), and IL-10 (H). (I–K) The relative protein expression level of P-NF-κB and NF-κB. Ctrl, piglets were given a basal diet and were challenged with saline; Si, piglets were given a silybin-supplemented diet and were challenged with saline; PQ, piglets were given a basal diet and were challenged with paraquat; Si + PQ, piglets were given a silybin-supplemented diet and were challenged with paraquat; TNF-α, tumor necrosis factor-α; IL, interleukin; NF-κB, nuclear factor-kB; P-NF-κB, phosphorylated NF-κB. Data are expressed as mean ± standard error (n = 6). * p < 0.05, ** p < 0.01.