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. 2024 Mar 21;73(11):239–244. doi: 10.15585/mmwr.mm7311a2

TABLE 2. Incidence* of coccidioidomycosis, histoplasmosis, and blastomycosis, by selected patient characteristics — United States, 2019–2021.

Characteristic Incidence* (95% CI)
Coccidioidomycosis
Histoplasmosis§
Blastomycosis
2019 2020 2021 2019 2020 2021 2019 2020 2021
Sex
Female
14.1
(14.1–14.7)
12.4
(12.2–12.7)
12.6
(12.4–12.9)
1.3
(1.2–1.4)
1.1
(1.0–1.2)
1.6
(1.5–1.8)
0.5
(0.4–0.6)
0.3
(0.2–0.4)
0.6
(0.5–0.7)
Male
15.8
(15.5–16.2)
14.1
(13.8–14.4)
15.0
(14.7–15.3)
1.8
(1.6–1.9)
1.7
(1.6–1.8)
2.3
(2.2–2.5)
1.2
(1.0–1.4)
1.3
(1.2–1.5)
1.1
(0.9–1.2)
Age group, yrs
<5
0.8
(0.7–1.1)
0.9
(0.7–1.2)
0.5
(0.4–0.7)
0.1
(0.1–0.3)
0.3
(0.2–0.5)
0.2
(0.1–0.4)
0.1
(0–0.5)
0.1
(0–0.4)
0
(—)
5–19
4.9
(4.7–5.2)
4.0
(3.7–4.2)
3.6
(3.4–3.9)
0.7
(0.6–0.9)
0.8
(0.7–1.0)
1.2
(1.0–1.4)
0.4
(0.3–0.6)
0.5
(0.3–0.7)
0.3
(0.2–0.5)
20–39
12.9
(12.6–13.3)
11.9
(11.5–12.2)
11.6
(11.2–11.9)
1.5
(1.3–1.7)
1.2
(1.1–1.4)
2.0
(1.8–2.2)
1.0
(0.8–1.2)
0.7
(0.6–1.0)
0.6
(0.5–0.9)
40–64
19.8
(19.3–20.2)
18.0
(17.6–18.4)
18.9
(18.5–19.4)
2.0
(1.9–2.2)
1.8
(1.7–2.0)
2.5
(2.3–2.7)
1.0
(0.8–1.2)
1.1
(0.9–1.4)
1.2
(1.0–1.4)
65–79
27.3
(26.6–28.1)
27.5
(26.7–28.3)
27.6
(26.8–28.4)
2.1
(1.9–2.5)
2.2
(2.0–2.6)
2.7
(2.4–3.1)
1.1
(0.8–1.5)
1.2
(0.9–1.6)
1.4
(1.1–1.9)
≥80
26.2
(24.8–27.7)
23.8
(22.5–25.1)
30.0
(28.6–31.6)
1.1
(0.8–1.6)
0.8
(0.5–1.2)
1.5
(1.1–2.0)
0.5
(0.2–1.1)
0.6
(0.3–1.3)
0.7
(0.4–1.4)
Race and ethnicity
AI/AN, NH
17.4
(15.3–19.7)
18.4
(16.2–20.8)
25.6
(22.7–28.9)
1.2
(0.5–3.2)
2.4
(1.1–5.0)
2.0
(0.8–5.4)
4.5
(2.4–8.4)
5.0
(2.7–9.3)
6.1
(3.0–12.1)
Asian and NH/OPI, NH
4.6
(4.2–5.0)
3.4
(3.1–3.8)
5.8
(5.4–6.3)
1.0
(0.7–1.5)
0.6
(0.3–0.9)
0.9
(0.6–1.3)
1.6
(1.1–2.4)
2.0
(1.3–3.1)
0.8
(0.4–1.6)
Black or African American, NH
4.0
(3.7–4.4)
3.9
(3.6–4.3)
5.9
(5.5–6.4)
0.9
(0.7–1.1)
1.0
(0.8–1.2)
1.4
(1.2–1.7)
0.6
(0.4–1.0)
0.7
(0.5–1.0)
0.5
(0.3–0.8)
White, NH
4.1
(4.0–4.2)
4.4
(4.3–4.6)
5.9
(5.7–6.0)
1.3
(1.2–1.4)
1.2
(1.1–1.3)
1.7
(1.6–1.9)
0.7
(0.4–1.2)
0.7
(0.6–0.8)
0.8
(0.7–0.9)
Hispanic or Latino
(all races)
11.2
(10.8–11.6)
9.8
(9.5–10.2)
12.5
(12.1–12.9)
1.2
(0.9–1.5)
0.8
(0.6–1.0)
1.0
(0.8–1.3)
0.9
(0.8–1.1)
1.1
(0.7–1.7)
0.8
(0.5–1.3)
Other**
4.6
(4.0–5.3)
5.2
(4.7–5.8)
8.6
(8.0–9.3)
1.9
(1.3–2.6)
1.1
(0.8–1.6)
1.3
(0.9–1.7)
0.2
(0–1.4)
0.1
(0–0.6)
0.1
(0–0.6)
Total 15.1
(14.9–15.3)
13.1
(12.9–13.2)
13.8
(13.6–14.0)
1.6
(1.5–1.7)
1.4
(1.3–1.5)
2.0
(1.9–2.1)
0.8
(0.7–0.9)
0.8
(0.7–0.9)
0.8
(0.7–0.9)

Abbreviations: AI/AN = American Indian or Alaska Native; NH = non-Hispanic; NH/OPI = Native Hawaiian or other Pacific Islander.

* Cases per 100,000 population. Summed state-specific denominators from 2019–2021 U.S. Census Bureau data were used to calculate incidence for the total grouping for each year.

Sex was missing for 68 cases, age was missing for 65 cases, and race and ethnicity were missing for 20,749 cases.

§ Sex was missing for five cases, age was missing for five cases, and race and ethnicity were missing for 497 cases.

Race and ethnicity were missing for 48 cases.

** Calculated on the basis of two or more reported race categories.