Table 1.

Summary of gene polymorphisms which might impact CLZ treatment.

Gene	Variant	Genotype/Allele	Predicted Phenotype	Reference
DRD2	rs1800497 (Taq1A)	A1/A1 or T/T *A1 allele or T allele	Better response CLZ	[18]
HTR2A	rs6313 (T102C)	C/C C allele	Non-response CLZ	[20,21]
HTR2A	rs6314 (C1354T or His452Tyr)	T/T T allele or 452Tyr	Non-response CLZ	[26,27,28]
SLC6A4	rs4795541	S/S or S allele	Non-response CLZ	[29]
SLC6A4	rs25531	G/G or G allele	Non-response CLZ	[29]
CYP1A2	rs7625521	*1F/*1F or A/A A or *1F allele	Low CLZ plasma and non-response	[33]
ABCB1	rs1045642 (C3435T)	T/T or T allele	High CLZ plasma and better response	[34]
ABCB1	rs2032582 (G2677T)	T/T or T allele	High CLZ plasma and better response	[34]