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. 2024 Mar 7;12(3):597. doi: 10.3390/biomedicines12030597

Table 3.

Clinical characteristics between patients who respond to only CLZ (CLZ-TRS) and those requiring augmentation strategies (CLZ-UTRS).

Variables CLZ Only
(CLZ-TRS) n = 49
Mean (S.D)
CLZ + Augmentation Strategies
(CLZ-UTRS) n = 51
Mean (S.D)
p Value
CLZ dose (mg/day) 306.75 (167.87) 365.13 (135.16) 0.033 *
CLZ plasma levels (ng/mL) 354.6 (187.01) 476.6 (169.14) <0.001 **
NCLZ plasma levels (ng/mL) 217.0 (118.07) 284.9 (79.21) <0.001 **
Wellbeing (SWEMWBS) score 25.21 (4.90) 22.62 (4.07) 0.003 *
Genal functioning (GAF) score 74.46 (13.14) 71.96 (9.76) 0.141
PANSS-positive 11.58 (3.96) 14.93 (4.42) <0.001 **
BNSS overall score 20.62 (15.54) 25.39 (15.09) 0.072
  • BNSS Motivation and Pleasure Factor

13.47 (9.10) 15.42 (9.44) 0.160
  • BNSS Expression factor

7.15 (7.48) 9.98 (7.38) 0.037 *

* p < 0.05. ** p < 0.001.