MMP 1	MMP 1 (or collagenase-1) is the prototypical MMP, functioning primarily to degrade collagen types 1 and 3.
MMP 9	MMP 9, also known as 92 kDa type IV collagenase, 92 kDa gelatinase, or gelatinase B (GELB), is a matrixin, a class of enzymes that belong to the zinc metalloproteinases family involved in the degradation of the extracellular matrix.
TIMP 1	TIMP 1, a tissue inhibitor of metalloproteinases, is a glycoprotein with a molecular weight of 28 kDa and is a natural inhibitor of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix.
TIMP 2	TIMP 2 is a natural inhibitor of MMP, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. It is critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors.
ECM	ECM = extracellular matrix.
TNFα	Tumor necrosis factor (TNF, cachexin, or cachectin, formerly known as tumor necrosis factor-alpha or TNF-α) is an adipokine and a cytokine. TNF is a member of the TNF superfamily, which consists of various transmembrane proteins with a homologous TNF domain.
ROS	ROS = reactive oxygen species.
HIF	Hypoxia-inducible factors (HIFs) are transcription factors that respond to decreases in available oxygen in the cellular environment or hypoxia.