Table 2.
Clinical features of responders and non-responders at baseline.
| Responder (% of All Patients) |
Non-Responder (% of All Patients) |
||
|---|---|---|---|
| N (%) | p 1 | ||
| EM | 13 (17%) | 3 (4%) | 0.586 |
| CM | 43 (56%) | 18 (23%) | |
| Patients with MOH | 34 (44%) | 9 (12%) | 0.981 |
| Patientes without MOH | 22 (28%) | 12 (16%) | |
| Median (75–25 percentiles) | p 2 | ||
| Age (years) | 50.00 (57–44) | 41.00 (49–36) | 0.082 |
|
Headaches frequency
(days/month) |
22.00 (30–14) | 30.00 (30–15) | 0.237 |
| MIDAS | 90.00 (129–67) | 99.00 (152–78) | 0.171 |
|
ASC-12
(raw data) |
6.00 (10–4) | 5.00 (12–3) | 0.812 |
|
ASC-12
(clinical score) |
Moderate (3–1) | Mild (3–1) | 0.628 |
|
GAD7
(raw data) |
8.00 (13–6) | 10.00 (14–6) | 0.491 |
|
GAD7
(clinical score) |
Mild (2–1) | Moderate (3–1) | 0.250 |
|
PHQ9
(raw data) |
7.50 (13–5) | 10.00 (14–6) | 0.132 |
|
PHQ9
(clinical score) |
Mild (2–1) | Moderate-Mild (2–1) | 0.259 |
| FSS | 45.00 (57–33) | 54.00 (59–39) | 0.151 |
1 Chi-Squared test; 2 U Mann–Whitney test; MIDAS: Migraine Disability Assessment Scale; FSS: Fatigue Severity Scale; ASC-12: Allodynia Symptom Checklist 12; GAD7: Generalized Anxiety Disorder 7; PHQ9: Patient Health Questionnaire 9; EM: episodic migraine; CM: chronic migraine; MOH: medication overuse headache; Clinical score:. Severe = 3; Moderate = 2; Mild = 1; Moderate-Mild = 1.5; Absent = 0.