Table 3.

Comparison of H₂O₂ and CAT values between the groups. A p-value of less than 0.05 was considered statistically significant (*—p < 0.05; **—p < 0.01).

Hydrogen Peroxide (H2O2)
	Before the initiation	52nd week
Control vs. MTX	p < 0.05 *	p < 0.05 *
Control vs. secukinumab	p < 0.05 *	p < 0.05 *
Control vs. ustekinumab	p < 0.05 *	p < 0.05 *
MTX vs. secukinumab	p > 0.05	p > 0.05
MTX vs. ustekinumab	p > 0.05	p > 0.05
Secukinumab vs. ustekinumab	p > 0.05	p > 0.05
Catalase (CAT)
Control vs. MTX	p < 0.01 **	p < 0.01 **
Control vs. secukinumab	p < 0.01 **	p < 0.01 **
Control vs. ustekinumab	p < 0.01 **	p < 0.01 **
MTX vs. secukinumab	p > 0.05	p < 0.05 *
MTX vs. ustekinumab	p > 0.05	p < 0.05 *
Secukinumab vs. ustekinumab	p > 0.05	p < 0.05 *

Abbreviations: MTX—methotrexate.