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Alignment of CXCR proteins. Residues of transmembrane domains (TMs), DRY motif (a highly conserved motif in family A GPCRs), and (semi)conserved cysteines are shaded in grey, red, and orange. TMs and (semi)conserved cysteines are defined from previous studies of salmon and teleost CXCRs [61,62]. The highly conserved NPxxY motif in family A GPCRs is observed in TM 7.
