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. 2024 Mar 21;16(6):1237. doi: 10.3390/cancers16061237
AML acute myeloid leukemia
AR androgen receptor
ASO antisense oligonucleotide
CAFS cancer-associated fibroblasts
CD4+/CD8+ TILs tumor-infiltrating CD4+/CD8+ T cells
COX-2 cyclooxygenase 2
CRC colorectal cancer
CRHR2 corticotropin-releasing hormone receptor 2
CRPC castration-resistant prostate cancer
CTLA-4 cytotoxic T-lymphocyte-associated protein-4
DC dendritic cell
DR5 death receptor 5
EGFR-TKI epidermal growth factor receptor tyrosine kinase inhibitor
EIF4F eukaryotic initiation factor 4F
EMT epithelial–mesenchymal transition
EZH2 enhancer of zeste homolog
FDA Food and Drug Administration
FDR false discovery rate
FGL1 fibrinogen-like protein 1
FP FGL1/PD-L1
GSK3β glycogen synthase kinase 3 beta
GRNA guide RNA
HCC hepatocellular carcinoma
HDAC histone deacetylase
HnRNP L heterogeneous nuclear ribonucleoprotein L
Id1 inhibitor of differentiation
IFN-γ interferon gamma
IL-2 interleukin 2
IL-6 interleukin 6
IL-8 interleukin 8
Inh-YY1 YY1 inhibitor
ISO isorhamnetin
JAK janus kinase
JNK jun N-terminal
LUAD MYH9 lung adenocarcinoma
mAbs monoclonal antibodies
MDSC myeloid-derived suppressor cell
MGF mammary gland factor
miRNA microRNA
MOR mu opioid receptor
mTOR mechanistic Target of Rapamycin
NF-κB nuclear factor kappa B
NK natural killer
NO nitric oxide
NOX4 NADPH oxidase 4
NSCLC non-small-cell lung cancer
PAI-1 plasminogen activator inhibitor 1 gene
PARP poly (ADP-ribose) polymerase
PAS pathway activity scores
PD-1 programmed death-1
PD-L1 programmed death ligand-1
PD-L2 programmed death ligand-2
PI3k/AKT phosphatidylinositol 3-kinase/protein kinase B
PTEN phosphatase and tensin homolog
PTM post-translational modification
RAS/MAPK Ras/mitogen-activated protein kinase
RKIP Raf kinase inhibitory protein
RPPA reverse-phase protein array
RTK receptor tyrosine kinase
sEVs small extracellular vesicles
SDS sodium dodecyl-sulfate
siRNA small interfering RNA
Sp1 specificity protein 1
STAT signal transducer and activator of transcription
T7-exo T7 peptide-decorated exosome
TAM tumor-associated macrophage
TCGA the cancer genome atlas
TCPA the cancer proteome atlas
TF transcription factor
TGF-β transforming growth factor-β
TIL tumor-infiltrating lymphocyte
TME tumor microenvironment
TMEM97 transmembrane protein 97
TNF-α tumor necrosis factor-alpha
TRAIL tumor necrosis factor-related apoptosis-inducing ligand
Treg regulatory T cell
Ucn2 Urocortin-2
YY1 Yin Yang 1