Table 4.
Characteristics | Number of Cases (%) |
---|---|
Follow up | |
Patients lost at follow-up | 4 (1%) |
Median (months)—total | 34.2 (32.2–36.1) |
Median (months)—p53abn | 22.2 (15.4–29.0) |
Median (months)—p53wt | 34.9 (32.9–36.8) |
Recurrence total | |
Yes | 13 (3.6%) |
No | 353 (96.4%) |
Recurrence p53abn | |
Yes | 2 (11.1%) |
No | 16 (88.9%) |
Recurrence p53wt | |
Yes | 11 (3.1%) |
No | 341 (96.3%) |
DFS p53abn patients | |
Median (months) | 21.8 (95% CI 15.4–29.0) |
DFS p53wt patients | |
Median (months) | 34.2 (95% CI 32.6–36.6) |
OS p53abn patients | |
Median (months) | 21.9 (95% CI 16.4–30.1) |
OS p53wt patients | |
Median (months) | 34.2 (95% CI 33.2–37.0) |
Last follow-up status | |
Alive without disease | 359 (98.1%) |
Alive with disease | 3 (0.8%) |
Dead of disease | 1 (0.3%) |
Dead of other cause | 3 (0.8%) |
Sites of recurrence | |
Vaginal cuff | 6 (46.1%) |
Isolated pelvic peritoneal | 2 (15.4%) |
Pelvic nodes | 1 (7.7%) |
Para-aortic nodes | 1 (7.7%) |
Isolated parenchymatous | 2 (15.4%) |
Extra abdominal | 1 (7.7%) |
Therapy at recurrence | |
RT | 4 (30.8%) |
CHT | 1 (7.7%) |
Surgery | 3 (23.0%) |
Surgery + RT | 4 (30.8%) |
Surgery + RT + CHT | 1 (7.7%) |
Response to therapy at recurrence | |
Complete response | 9 (69.2%) |
Partial response | 2 (15.4%) |
Stable disease | 1 (7.7%) |
Progression | 1 (7.7%) |
RT = radiotherapy; CHT = chemotherapy; DFS = disease-free survival; OS = overall survival.