Table 4.

Drugs and dosages used for pediatric OM

Drug	Dose	FDA approval age
Efinaconazole	Once daily Toenails 48 weeks	>6 years
Tavaborole	Once daily Toenails 48 weeks	>6 years
Ciclopirox solution	Once daily Toenails 48 weeks	>12 years
Terbinafine	250 mg tab:  • <20 kg-62.5 mg/day  • 20-40 kg-125 mg/day  • >40 kg-250 mg/day Terbinafine granules (125 mg or 187.5 mg packet)  • <25 kg 125 mg/day (1 packet of 125 mg)  • 25-35 kg 187.5 mg/day (1 packet of 187.5 mg)  • >35 kg 250 mg/day (2 packets of 125 mg)	Off-label use in OM. Terbinafine granules approved for tinea capitis in >4-year-old children
Itraconazole	5 mg/kg/day	Off label use in OM
Fluconazole	6 mg/kg/week	Off label use in OM FDA-approved for candidiasis in 6 months to 13 years of age