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. 2024 Mar 13;46(3):2402–2443. doi: 10.3390/cimb46030153
WHO World Health Organization
CNS Central nervous system
HGG high-grade gliomas
LGGs Low-Grade Gliomas
MRI Magnetic resonance imaging
GBM Glioblastom
IDH1 Isocitrate dehydrogenase 1
IHC Immunohistochemistry
UPS Ubiquitin proteasome system
AS Astrocytoma
ODG Oligodendroglioma
HDAC1 Histone deacetylase 1
NSCs Neural stem cells
GSCs Glioma stem cells
SVZ Subventricular zone
OPCs Oligodendrocyte progenitor cells
PUFAs Polyunsaturated fatty acids
NAC N-acetylcysteine
PE-PUFAs Phosphatidylethanolamine PUFA
BBB Blood-brain barrier
FasL Fas ligand
TAAs Tumor-associated antigens
MDSCs Myeloid-Derived Suppressor Cells
CSF-1 Colony Stimulating Factor-1
Arg1+ Arginase 1 positive
AEG1 Astrocyte elevated gene-1
TCGA The Cancer Genome Atlas
GTEx Genotype-Tissue Expression
CGGA Chinese Glioma Genome Atlas
MIF Macrophage migration inhibitory factor
PD-1 Programmed cell death protein 1
Tregs Regulatory T cells
Tfr T follicular regulatory
CTLA-4 Cytotoxic T-Lymphocyte Associated protein 4
PFG Permeability Factor G
NK Natural Killer
TGF-β Transforming Growth Factor Beta
NKG2D Natural-killer group 2, member D
IFN-γ Interferon Gamma
CAR-T Chimeric Antigen Receptor T
EGFRvIII EGFR variant III
IL-13Rα Interleukin-13 Receptor Alpha 2
TME Tumor microenviroment
Treg Regulatory T cell
TIM-3 T-cell immunoglobulin domain and mucin domain-3
DCs Dendritic cells
DIPG Diffuse Intrinsic Pontine Glioma
SRS Stereotactic Radiosurgery
CSCs Cancer stem cells
TAMs Tumor-associated macrophages
EVs Extracellular vesicles
CX-43 Connexin-43
JNK C-Jun N-terminal kinase
Grnd Grindelwald
Egr Eiger
BDNF Brain-derived neurotrophic factor
GPER G protein-coupled estrogen receptor
GICs Glioma-initiating cells
AQPs Aquaporins
EGFR Epidermal growth factor receptor
ABAT Aminobutyrate aminotransferase
PDGFRA Platelet-derived growth factor receptor alpha
RNA Ribonucleic acid
TFs Transcription factors
lncRNA Long non-coding RNA
DNA Deoxyribonucleic acid
PTMS Posttranslational modifications
SENP1 SUMO-specific protease
miRNA MicroRNA
DII1-4 Delta-like family
PKB Protein kinase B
PI3K PI3 kinase
ACSS2 Acetyl-CoA synthetase 2
SREBP Sterol regulatory element-binding protein-1
EOR Extent of resection
LOS Length of hospital day
CSR Complete surgical resection
IORT Intraoperative radiation therapy
IoMRI Intraoperative MRI
ECM Extracellular matrix
TREM2 Triggering receptor expressed on myeloid cells 2
CAFs Cancer-associated fibroblasts
FN1 Fibronectin
MDSCs Myeloid-Derived Suppressor Cells
VEGF Vascular endothelial growth factor
vWF Von Willebrand factor
B2R Bradykinin receptor-2
ICI Immune checkpoint inhibition
CAR Chimeric antigen receptor
oAds Oncolytic adenovirus
DIPG Diffuse Intrinsic Pontine Glioma
NSG NOD scid gamma
EGR Early growth response
ROS Reactive oxidative stress
ER Endoplasmic reticulum
IP3R Inositol triphosphate receptor
TTFields Tumor Treating Fields
CCNU Lomustine
MGMT Methyltransferase
DCVax-L Dendritic cell vaccination
nGBM Newly diagnosed glioblastoma
rGBM Recurrent glioblastoma
OS Overall survival
PD-1 Programmed cell death protein
PD-L1 Programmed cell death protein ligand 1
ncRNAs Non-coding RNAs
AI Artificial intelligence