Table 8.

Top 10 most significant and enriched resp. Molecular Function Gene Ontology (GO) terms out of a total of 193 that have been identified for the SKBR3 cell line. A complete list of significant and enriched GO terms in Table S10.

MF GO Term Analysis for SKBR3 Cell Line
Top 10 Most Significant MF			Top 10 Most Enriched MF
GO Terms			GO Terms
ID	Term	Adjusted p-Value	ID	Term	% Signif/All
GO:0003723	RNA binding	1.0 × ${10}^{-30}$	GO:0061608	nuclear import signal receptor activity	100.00
GO:0003735	structural constituent of ribosome	1.9 × ${10}^{-17}$	GO:0008097	5S rRNA binding	100.00
GO:0045296	cadherin binding	2.1 × ${10}^{-13}$	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	100.00
GO:0031625	ubiquitin protein ligase binding	5.5 × ${10}^{-13}$	GO:0140142	nucleocytoplasmic carrier activity	95.00
GO:0005524	ATP binding	2.2 × ${10}^{-9}$	GO:0000339	RNA cap binding	94.00
GO:0019899	enzyme binding	5.0 × ${10}^{-9}$	GO:0005123	death receptor binding	94.00
GO:0031492	nucleosomal DNA binding	4.6 × ${10}^{-8}$	GO:0031492	nucleosomal DNA binding	93.00
GO:0003697	singl-strandd DNA binding	8.4 × ${10}^{-8}$	GO:0030515	snoRNA binding	93.00
GO:0005525	GTP binding	2.0 × ${10}^{-7}$	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity	93.00
GO:0008565	protein transporter activity	2.3 × ${10}^{-7}$	GO:0003688	DNA replication origin binding	93.00