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In vitro and in vivo oncogenicity of HVS/Tip mSH3B
| Virus | No. with characteristic/no. tested
|
Survival (days) | ||
|---|---|---|---|---|
| In vitro immortalizationa | Virus recoveryb | In vivo lymphoma | ||
| None | 0/5 | |||
| HVS C488 | 23/24 | 2/2 | 2/2 | 19 and 20 |
| HVSΔTip | 0/9 | 2/2 | 0/2 | >370 |
| HVSΔTip-SV40-SEAP | 0/9 | 2/2 | 0/2 | >370 |
| HVS/Tip mSH3B | 12/12 | 2/2 | 2/2 | 20 and 21 |
Primary T-lymphocyte immortalization.
Virus was recovered from PBMCs of an infected marmoset as described previously (12).
