Table 4.
Prognostic value of NSVT and PVCs on new occurrence of VA/SCD and cardiac death
| New onset of adverse VA/SCD (n = 15) | Cardiac death (n = 71) | |||||
|---|---|---|---|---|---|---|
| Univariate | Univariate | Multivariate | ||||
| HR (95%CI) | P value | HR (95%CI) | P value | HR (95%CI) | P value | |
| NSVT | 13.57 (3.06–60.18) | <0.001 | 1.55 (0.96–2.51) | 0.073 | 1.16 (0.67–1.98) | 0.603 |
| PVC counts (ln) | 1.46 (1.15–1.86) | 0.002 | 1.09 (1.01–1.17) | 0.022 | 1.10 (1.02–1.19) | 0.019 |
| PVC burden (ln) | 1.43 (1.14–1.80) | 0.002 | 1.09 (1.01–1.17) | 0.022 | 1.10 (1.02–1.19) | 0.017 |
| Categorical PVC counts | ||||||
| Tertile 1st | Ref | Ref | Ref | |||
| Tertile 2nd | 2.18 (0.20–24.05) | 0.525 | 1.44 (0.76–2.71) | 0.262 | 1.42 (0.72–2.79) | 0.309 |
| Tertile 3rd | 15.37 (2.00–118.28) | 0.009 | 2.37 (1.31–4.29) | 0.004 | 2.33 (1.27–4.28) | 0.006 |
| Categorical PVC burden | ||||||
| Tertile 1st | Ref | Ref | Ref | |||
| Tertile 2nd | 2.10 (0.19–23.21) | 0.544 | 1.21 (0.64–2.27) | 0.557 | 1.41 (0.73–2.69) | 0.306 |
| Tertile 3rd | 15.78 (2.05–121.46) | 0.008 | 2.25 (1.25–4.02) | 0.007 | 2.58 (1.42–4.69) | 0.002 |
HR, Hazard ratio; CI, confidence interval; PVC, premature ventricular contraction; NSVT, non-sustained-ventricular tachycardia. Multivariate analysis included significant clinical parameters in univariate analysis (age, BMI, modified Mayo stage 2004, LVEF, cTnI, NT-proBNP, Serum Creatinine, BUN, LVPW thickness, eGFR, NYHA class III-IV) with a stepwise selection.