Table 1.
Biological characteristics of the healthy participants and patients’ groups.
| Healthy Participants (31) | Patients (37) | p | |
|---|---|---|---|
| Gender | 22 women; 9 men | 25 women; 12 men | 0.762 |
| Age | 40.71 ± 13.15 | 46.03 ± 15.43 | 0.135 |
| BMI (kg/m2) | 23.00 ± 3.73 | 23.89 ± 3.80 | 0.345 |
| TC (mM) | 4.75 ± 0.64 | 8.06 ± 1.40 | <0.0001 *** |
| HDL-C (mM) | 1.62 ± 0.42 | 1.60 ± 0.35 | 0.807 |
| LDL-C (mM) | 2.68 ± 0.56 | 5.90 ± 1.29 | <0.0001 *** |
| TG (mM) | 1.02 ± 0.48 | 1.24 ± 0.55 | 0.095 |
| apoB (mM) | 0.78 ± 0.14 | 1.51 ± 0.27 | <0.0001 *** |
| Lp(a) (g/L) | 0.24 ± 0.22 | 0.29 ± 0.32 | 0.509 |
| CRP (mg/L) | 1.37 ± 2.29 | 2.29 ± 3.87 | 0.251 |
| Hcy (µM) | 11.28 ± 3.72 | 11.34 ± 3.64 | 0.953 |
| Neutrophils (N) (109/L) | 3.87 ± 1.33 | 3.77 ± 1.82 | 0.803 |
| Lymphocytes (L) (109/L) | 2.06 ± 0.36 | 1.86 ± 0.61 | 0.180 |
| NLR (N/L) | 1.96 ± 0.71 | 2.22 ± 1.28 | 0.328 |
| Albumin (g/L) | 42.59 ± 2.61 | 43.97 ± 3.15 | 0.069 |
| Transferrin (g/L) | 2.62 ± 0.49 | 2.27 ± 0.32 | 0.001 ** |
| Iron (µM) | 18.53 ± 9.88 | 15.60 ± 5.00 | 0.168 |
| FCT (µM) | 65.48 ± 12.23 | 56.97 ± 8.09 | 0.002 * |
| TSC (%) | 27.30 ± 13.44 | 28.61 ± 7.70 | 0.656 |
| Ferritin (µg/L) | 57.81 ± 56.11 | 102.04 ± 110.45 | 0.045 * |
| Haptoglobin (g/L) | 1.04 ± 0.35 | 1.16 ± 0.50 | 0.291 |
| Orosomucoid (g/L) | 0.62 ± 0.17 | 0.67 ± 0.21 | 0.361 |
| Prealbumin (g/L) | 0.28 ± 0.05 | 0.28 ± 0.05 | 0.920 |
Data are mean ± SD. Mean dates were compared between patients with hypercholesterolemia (HC) and healthy participants (HP). p ≤ 0.0001 ***, p ≤ 0.001 **, p ≤ 0.05 * are significant. BMI, body mass index, kg/m2; TC, total cholesterol; HDL-C, HDL-cholesterol; LDL-C, LDL-cholesterol; TG, triglycerides; apoB, Apoliprotein B; Lp(a), lipoprotein(a); CRP, C-reactive protein; Hcy, homocystein; NLR, neutrophils-lymphocytes ratio; FCT, iron fixation capacity of transferrin; TSC, transferrin saturation coefficient.