Table 2.
Compound | IC50 (µM) 1 | |||||
---|---|---|---|---|---|---|
MDA-MB-231 | MCF-7 | HepG2 | ||||
Normo | Hypo | Normo | Hypo | Normo | Hypo | |
5c | 48.10 ± 3.23 | 46.23 ± 3.93 | 34.33 ± 2.85 | 28.12 ± 1.72 | 61.36 ± 5.75 | 69.43 ± 5.16 |
5h | 75.25 ± 6.81 | 81.2 ± 7.34 | 63.84 ± 5.57 | 57.43 ± 5.50 | 81.41 ± 7.03 | 80.41 ± 7.14 |
6c | 56.34 ± 4.19 | 61.56 ± 5.13 | 50.44 ± 4.73 | 47.04 ± 4.01 | 68.78 ± 4.17 | 62.78 ± 5.52 |
6h | 54.23 ± 4.87 | 50.35 ± 4.27 | 41.36 ± 2.22 | 30.31 ± 3.14 | 58.23 ± 5.45 | 54.33 ± 5.15 |
Staurosporine | 10.30 ± 0.51 | 10.55 ± 0.84 | 7.81 ± 0.59 | 7.65 ± 0.73 | 18.71 ± 1.45 | 17.78 ± 0.97 |
1 IC50 values represent an average of at least three independent experiments.