Cross-Omic Transcription Factor Analysis: An Insight on Transcription Factor Accessibility and Expression Correlation

. 2024 Feb 21;15(3):268. doi: 10.3390/genes15030268

Algorithm 1: Footprint score computation

1:
for m in M do ▹ $m \to$ is a single motif/TF
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Compute the footprint signal vector ${FP}_{m} = [f p_{1}, \dots, f p_{n}]$
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end for
4:
for c in C do ▹ $c \to$ is a single cell
5:
for m in M do
6:
Compute the footprint score ${TFP}_{m \times c}$
7:
end for
8:
end for
9:
for $c t$ in $C T$ do ▹ $c t \to$ is a single cell type
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for m in M do
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Compute ${TFP}_{m, c t}$ the average footprint score of m $\forall c \in c t$
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end for
13:
end for