Figure 1.

Total CATB levels in supernatants of MDM selected for TMT proteomics. MDM were cultured for 7 days and infected with HIV-1_ADA. At day 1 post-infection (pi), MDM were treated with JWH-133 (0.5 μM) or vehicle control, and cultures were maintained until day 13 post-infection, replacing half of media with fresh media containing JWH-133 treatment every three days. Uninfected MDM treated with vehicle were used as controls. At day 13 pi, supernatants and lysates were collected. Total CATB levels were measured by ELISA. The percent change in total CATB levels compared to the uninfected vehicle-treated control per donor was calculated. The mean ± standard error of the mean (SEM) is shown. * p < 0.05.