| Outcome | No. of Studies (Participants) | Risk of Bias | Inconsistency | Imprecision | Indirectness | Publication Bias | Pooled Effect Estimate | Certainty of Evidence |
| Headache disorders | ||||||||
| Pain intensity | 2 (110) | Very serious a | None | Serious c | None | Begg test: 0.29 Egger test: 0.01 |
MD: −0.79 (−1.39, −0.20) | Very low |
| Headache impact | 2 (60) | Very serious a | None | Serious c | Serious d | No suspected | SMD: 0.02 (−0.44, 0.48) | Very low |
| Low back pain | ||||||||
| Pain intensity | 2 (123) | Very serious a | Very serious b | Serious c | None | No suspected | SMD: −1.68 (−3.89, 0.52) | Very low |
| Infant colic | ||||||||
| Crying time | 2 (82) | Very serious a | Very serious b | Serious c | Serious d | No suspected | MD: −1.78 (−4.01, 0.44) | Very low |
| Sleeping time | 2 (82) | Very serious a | Very serious b | Serious c | Serious d | No suspected | MD: 1.77 (−0.12, 3.66) | Very low |
| MD: mean difference; SMD: standardized mean difference. a Risk of bias was downgraded because more than 50% of the studies included presented fair or low methodological quality. b Inconsistency was downgraded because I2 was higher than 75%. c Imprecision was downgraded because the interventions were heterogeneous. d Indirectness was downgraded because the number of patients was <100. | ||||||||
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