Figure 2.

Scans of histology slides in undifferentiated carcinoma with osteoclast-like giant cells (UCOGC) of the pancreas and its variants, stained with hematoxylin and eosin and anti-PD-L1 antibody: (a,b) pure UCOGC with diffuse strong PD-L1 positivity (40×), (c,d) UCOGC combined with pancreatic ductal adenocarcinoma (PDAC), note the PD-L1-positive UCOGC and negative PDAC component (40×), (e,f) UCOGC combined with intraductal papillary mucinous neoplasm (IPMN), note the PD-L1-positive UCOGC and negative IPMN (20×), (g,h) PDAC component in combined UCOGC-PDAC with PD-L1 negativity, positivity only in macrophages (40×).