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. 2024 Mar 14;25(6):3285. doi: 10.3390/ijms25063285

Table 2.

Summary of genomic articles focused on UCOGC DNA mutational profiles obtained from FFPE tissue.

Authors Year UCOGC n= Method Mutated Genes (Pathogenic), Number of Cases
Present study 2024 13 Illumina MiSeq, NGS custom panel 10× KRAS, 9× TP53, 4× CDKN2A, 1× SMAD4, CIC, GNAS, APC, ATM, NF1, FBXW7, ATR, FGFR3
Yang et al. [27] 2020 1 Whole exome sequencing KRAS, 1× BRCA2
Luchini et al. [6] 2017 8 Illumina HiSeq, whole exome sequencing KRAS, 7× TP53, 3× TTN, 2× CDKN2A, SERPINA3, MAGEB4, GLI3, MEGF8, 1× SMAD4
Lukáš et al. [23] 2006 2 PCR KRAS wild type, 2× TP53 wild type
Sedivy et al. [28] 2005 1 PCR KRAS
Sakai et al. [24] 2000 3 PCR KRAS
Imai et al. [21] 1999 3 PCR KRAS
Deckard-Janatpour et al. [22] 1998 6 PCR KRAS
Westra et al. [25] 1998 5 PCR KRAS
Hoorens et al. [26] 1998 1 PCR KRAS