Figure 5.

Obesity reduces locomotion in both sexes and alters behavior in female mice. Total distance traveled during the open field test is shown for males (A) and females (G). Percentage of time spent in the center of the open field is shown for males (B) and females (H). Distance traveled in the Y-maze is shown for males (C) and females (I). Y-maze performance, as measured by % alternation triplets, is shown for males (D) and females (J). Total distance traveled in the Morris water maze is shown for males (E) and females (K). Morris water maze performance, as assessed by percentage of distance in the target quadrant, is shown for males (F) and females (L). ** p < 0.01; *** p < 0.001; **** p < 0.0001.