Table 1.

Body weight and peripheral metabolic characteristics.

	Males		Females
	WT	ob/ob	WT	ob/ob
Body weight (g)	29.5 ± 2.7	51.5 ± 3.3 *	20.6 ± 1.4	52.4 ± 4.2 *
Glucose (mg/dL)	157.4 ± 32.6	175.6 ± 41.6	126.3 ± 18.5	177.7 ± 54.3 *
GTT AUC (mg * min/dL)	29,500 ± 5380	43,307 ± 8706 *	23,323 ± 2106	47,047 ± 8270 *
Insulin (pg/mL)	229.1 ± 131.7	3311.4 ± 1625.2 *	182.2 ± 78.7	3769.2 ± 729.6 *
Total cholesterol (mg/dL)	124.1 ± 35.9	279.1 ± 25.9 *	77.0 ± 17.8	290.5 ± 15.9 *

Data shown are mean ± standard deviation. * p < 0.05 compared to sex-matched WT mice. GTT AUC: glucose tolerance test area under the curve.