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. 2024 Mar 19;25(6):3461. doi: 10.3390/ijms25063461

Figure 4.

Figure 4

(A) Western blot bands (n = 1 per lane) and quantitative analyses of TRL4 and IκBα in the CA1 field extracted from the Veh-sham, AU-sham, Veh-IR, and AU-IR groups at 1 day after cerebral IR. IR upregulates TLR4 and downregulates IκBα, but AU treatment prevents it. (B) Western blot bands (n = 1 per lane) and quantitative analyses of NF-κB p65 in the nuclear and cytoplasmic fractions of the CA1 field obtained from the Veh-sham, AU-sham, Veh-IR, and AU-IR groups at 1 day after cerebral IR. IR apparently induces the nuclear-cytoplasmic translocation of NF-κB p65, but AU mitigates it. Note that Western blot bands for n = 4 are included in the Supplementary Materials Figures S5–S12. The error bars represent mean ± SD (n = 5/group; * p < 0.05 vs. corresponding sham group, # p < 0.05 vs. Veh-IR group).