Table 1.

Demographic characteristics of post-menopausal women on HRT (cohort 1) and post-menopausal women not on HRT (cohort 2).

Cohort 1 (N = 78,192) and Cohort 2 (N = 1,604,822) before Propensity Matching						Cohort 1 (N = 67,874) and Cohort 2 (N = 67,874) after Propensity Matching
	Cohort	Mean ± SD	Patients	%Cohort	p-Value	SD	Mean ± SD	Patients	%Cohort	p-Value	SD
Age at Index	1	57.9 ± 6.7	67,874	100%	<0.001	0.735	57.9 ± 6.7	67,874	100%	0.992	<0.001
	2	63.7 ± 8.9	1,578,637	100%			57.9 ± 6.7	67,874	100%
Female	1		67,874	100%	-	-		67,874	100%	-	-
	2		1,578,637	100%				67,874	100%
White	1		54,710	80.6%	<0.001	0.202		54,710	80.6%	1	<0.001
	2		1,137,542	72.1%				54,710	80.6%
Not Hispanic/Latino	1		51,502	75.9%	<0.001	0.189		51,502	75.9%	1	<0.001
	2		1,064,194	67.4%				51,502	75.9%
Black or African American	1		3815	5.6%	<0.001	0.198		3815	5.6%	0.962	<0.001
	2		174,524	11.1%				3819	5.6%
Hispanic or Latino	1		2860	4.2%	<0.001	0.141		2860	4.2%	0.925	0.001
	2		118,797	7.5%				2853	4.2%
Asian	1		1626	2.4%	<0.001	0.082		1626	2.4%	1	<0.001
	2		60,399	3.8%				1626	2.4%
American Indian/Alaska Native	1		141	0.2%	0.373	0.004		141	0.2%	0.764	0.002
	2		3540	0.2%				136	0.2%
Native Hawaiian/Pacific Islander	1		79	0.1%	<0.001	0.052		79	0.1%	1	<0.001
	2		5892	0.4%				79	0.1%
BMI	1	26.8 ± 5.8	32,415	47.8%	<0.001	0.402	26.8 ± 5.8	32,424	47.8%	0.987	<0.001
	2	29.3 ±6.8	395,212	25.0%			28.9 ± 6.8	32,421	47.8%
Hgb A1c	1	5.7 ± 1.1	17,710	26.1%	<0.001	0.405	5.7 ± 1.1	17,711	26.1%	0.985	0.172
	2	6.3 ± 1.6	415,386	26.3%			6.0 ± 1.4	17,708	26.1%
Diabetes Mellitus	1		5051	7.4%	<0.001	0.256		5051	7.4%	0.967	<0.001
	2		245,285	15.5%				5047	7.4%

Abbreviations: Body mass index (BMI), hemoglobin A1c (Hgb A1c), standard deviation (SD), hormone replacement therapy (HRT).