Table 2.
Main echocardiographic measurements in both study groups.
| HCM (n = 30) | ATTR (n = 30) | p Value | |
|---|---|---|---|
| LV end-diastolic volume index, mL/m2.7 | 51.4 [37.9–59.8] | 49.7 [38.7–60.0] | 0.831 |
| LV end-systolic volume index, mL/m2.7 | 18.8 [15.0–25.9] | 23.2 [17.2–27.1] | 0.020 |
| LV ejection fraction, % | 63.4 [54.4–63.8] | 55.0 [52.3–57.2] | <0.001 |
| Stroke volume index, mL/m2.7 | 32.5 [23.2–36.3] | 27.8 [21.5–31.8] | 0.444 |
| Cardiac output, L/min | 3.9 [2.8–4.4] | 3.4 [2.4–3.7] | 0.004 |
| Ventricular septum thickness, mm | 15.2 [14.6–18.0] | 15.5 [14.0–21.0] | 0.688 |
| Mitral E/tissue E’ velocity ratio | 11.7 ± 5.0 | 16.8 ± 5.9 | 0.001 |
| Global longitudinal strain, % | 15.0 [16.0–10.3] | 12.5 [14.5–10.0] | 0.022 |
| Global myocardial work index, mm Hg% | 1468.5 ± 403.5 | 1149.7 ± 319.3 | 0.001 |
| Global constructive work, mm Hg% | 1442 [989–1554] | 1141 [874–1356] | 0.008 |
| Left atrial volume index, mL/m2.7 | 43.7 ± 16.2 | 44.6 ± 15.5 | 0.991 |
| SVR (corrected), dyne/s/cm−5 | 1899 [1693–2600] | 2168 [2051–2860] | 0.008 |
Measurements are expressed as mean values ± SD or median values [IQR], as appropriate. LV, left ventricle/ventricular; SVR, systemic vascular resistance.