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(A) Structure diagrams of selected compounds in the different ligand groups. (B) Two potent mast cell degranulators: monomer C48/80 and tetrahydroisoquinoline (THIQ) motif. Molecular fragments with patterns similar to monomer of C48/80 as well as heterocyclic motifs from THIQ are highlighted (created with ChemOffice 22.0, Perkin Elmer, Shelton, CT, USA).
