Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Binding of IL-6/sIL-6R to gp130 results in the IL-6 trans-signaling. This initiates activation of the downstream intracellular signaling cascade via the JAK/STAT3 pathway leading to IL-6-mediated inflammatory responses. Created with biorender.com.
