Table 2.
Phase transition thermodynamic parameters (Tp, ΔT1/2, ΔHp, Tm, ΔT1/2 and ΔH) for DMPC MLVs, with DMSO added to already formed liposomes, using DMSO contents between 0–40% (v/v) a.
XDMSO | % DMSO (v/v) | Tp/°C | ΔT1/2/°C | ΔHp kJ·mol−1 |
Tm/°C | ΔT1/2/°C | ΔH kJ·mol−1 |
---|---|---|---|---|---|---|---|
0 | 0 | 13.0 | 2.2 | 2 | 23.9 | 0.6 | 21 |
0.013 | 5.0 | 13.2 | 2.7 | 3 | 24.2 | 0.6 | 21 |
0.027 | 10 | 15.2 | 3.3 | 3 | 24.4 | 0.7 | 20 |
0.060 | 20 | 17.9 | 3.8 | 2 | 25.2 | 1.2 | 17 |
0.098 | 30 | 21.5 | 3.8 | 2 | 26.1 | 1.3 | 16 |
0.14 | 40 | --- | --- | --- | 28.2 | 2.0 | 15 |
a The estimated uncertainty is ±0.2 °C for the transition temperature, ±0.2 °C for the half width at half height, and ±1.5 kJ·mol−1 for ΔH.