Table 3.
The top five important features and the proportion of model variance explained by each feature.
| Adverse Health Event | Gender | Fea. Rank. | Three Year | Five Year | Ten Year | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Model 2 | Model 3 | Model 4 | Model 2 | Model 3 | Model 4 | Model 2 | Model 3 | Model 4 | ||||||||||||
| Mortality | Male | 1 | AGE | (0.816) | AGE | (0.780) | AGE | (0.646) | AGE | (0.863) | AGE | (0.832) | AGE | (0.729) | AGE | (0.910) | AGE | (0.850) | AGE | (0.769) |
| 2 | WT | (0.056) | WT | (0.051) | HGB | (0.050) | WT | (0.046) | WT | (0.043) | HGB | (0.045) | SMK | (0.022) | WT | (0.030) | HGB | (0.027) | ||
| 3 | BMI | (0.036) | BMI | (0.032) | AST | (0.035) | SMK | (0.024) | FBS | (0.028) | GGT | (0.034) | WT | (0.022) | FBS | (0.025) | GGT | (0.024) | ||
| 4 | PA | (0.026) | FBS | (0.030) | GGT | (0.032) | BMI | (0.022) | SMK | (0.023) | WT | (0.029) | BMI | (0.021) | SMK | (0.022) | WT | (0.023) | ||
| 5 | SMK | (0.024) | PA | (0.022) | WT | (0.031) | PA | (0.019) | BMI | (0.021) | FBS | (0.020) | PA | (0.010) | BMI | (0.020) | AST | (0.019) | ||
| Female | 1 | AGE | (0.875) | AGE | (0.840) | AGE | (0.723) | AGE | (0.906) | AGE | (0.873) | AGE | (0.706) | AGE | (0.853) | AGE | (0.858) | AGE | (0.776) | |
| 2 | WT | (0.036) | WT | (0.035) | HGB | (0.051) | WT | (0.025) | WT | (0.025) | HGB | (0.039) | BMI | (0.039) | FBS | (0.030) | HGB | (0.020) | ||
| 3 | BMI | (0.030) | FBS | (0.029) | GGT | (0.046) | BMI | (0.021) | FBS | (0.023) | GGT | (0.038) | WT | (0.025) | WT | (0.024) | FBS | (0.018) | ||
| 4 | PA | (0.027) | BMI | (0.026) | WT | (0.030) | PA | (0.016) | HT | (0.016) | FBS | (0.024) | WC | (0.024) | BMI | (0.019) | GGT | (0.018) | ||
| 5 | WC | (0.010) | PA | (0.025) | FBS | (0.024) | WC | (0.013) | DBP | (0.015) | WT | (0.024) | PA | (0.021) | WC | (0.014) | WT | (0.017) | ||
| Heart disease | Male | 1 | AGE | (0.739) | AGE | (0.683) | AGE | (0.617) | AGE | (0.869) | AGE | (0.835) | AGE | (0.819) | AGE | (0.809) | AGE | (0.767) | AGE | (0.734) |
| 2 | BMI | (0.071) | BMI | (0.045) | WC | (0.042) | WC | (0.060) | WC | (0.047) | WC | (0.029) | WC | (0.067) | BMI | (0.037) | WC | (0.054) | ||
| 3 | WC | (0.061) | SBP | (0.041) | BMI | (0.038) | BMI | (0.045) | BMI | (0.036) | FH_HT | (0.029) | BMI | (0.053) | WT | (0.033) | BMI | (0.033) | ||
| 4 | PA | (0.027) | WC | (0.039) | SBP | (0.030) | SMK | (0.009) | SBP | (0.029) | BMI | (0.027) | SMK | (0.030) | FBS | (0.033) | SBP | (0.029) | ||
| 5 | SMK | (0.026) | WT | (0.034) | FBS | (0.028) | FH_HT | (0.008) | FBS | (0.018) | SBP | (0.024) | HT | (0.011) | WC | (0.033) | FBS | (0.029) | ||
| Female | 1 | AGE | (0.890) | AGE | (0.851) | AGE | (0.824) | AGE | (0.890) | AGE | (0.851) | AGE | (0.824) | AGE | (0.857) | AGE | (0.819) | AGE | (0.786) | |
| 2 | SMK | (0.184) | WC | (0.044) | WC | (0.045) | SMK | (0.184) | WC | (0.044) | WC | (0.045) | BMI | (0.043) | SBP | (0.035) | SBP | (0.029) | ||
| 3 | WC | (0.051) | SBP | (0.039) | DBP | (0.021) | WC | (0.051) | SBP | (0.039) | DBP | (0.021) | WC | (0.037) | WC | (0.033) | BMI | (0.024) | ||
| 4 | BMI | (0.021) | BMI | (0.020) | SBP | (0.021) | BMI | (0.021) | BMI | (0.020) | SBP | (0.021) | WT | (0.021) | BMI | (0.031) | WC | (0.023) | ||
| 5 | WT | (0.016) | FBS | (0.014) | BMI | (0.017) | WT | (0.016) | FBS | (0.014) | BMI | (0.017) | SMK | (0.015) | FBS | (0.021) | GGT | (0.020) | ||
| Stroke | Male | 1 | AGE | (0.973) | AGE | (0.957) | AGE | (0.948) | AGE | (0.923) | AGE | (0.896) | AGE | (0.866) | AGE | (0.934) | AGE | (0.915) | AGE | (0.892) |
| 2 | WC | (0.014) | SBP | (0.011) | SBP | (0.009) | WC | (0.023) | FBS | (0.019) | FBS | (0.014) | WC | (0.024) | WC | (0.014) | WC | (0.016) | ||
| 3 | SMK | (0.004) | FBS | (0.008) | FBS | (0.008) | SMK | (0.011) | SBP | (0.016) | SBP | (0.013) | SMK | (0.010) | SBP | (0.011) | SBP | (0.010) | ||
| 4 | BMI | (0.004) | DBP | (0.007) | WC | (0.006) | PA | (0.011) | WC | (0.015) | WC | (0.012) | DRK | (0.007) | FBS | (0.011) | FBS | (0.009) | ||
| 5 | PA | (0.003) | PA | (0.005) | DBP | (0.005) | BMI | (0.011) | SMK | (0.010) | GGT | (0.010) | FH_STR | (0.007) | HT | (0.011) | DBP | (0.008) | ||
| Female | 1 | AGE | (0.929) | AGE | (0.901) | AGE | (0.877) | AGE | (0.917) | AGE | (0.889) | AGE | (0.860) | AGE | (0.973) | AGE | (0.960) | AGE | (0.950) | |
| 2 | WC | (0.022) | SBP | (0.019) | SBP | (0.017) | WC | (0.021) | SBP | (0.019) | SBP | (0.014) | WC | (0.009) | SBP | (0.009) | SBP | (0.008) | ||
| 3 | BMI | (0.015) | WC | (0.013) | WC | (0.011) | BMI | (0.018) | WC | (0.017) | TG | (0.013) | BMI | (0.008) | FBS | (0.008) | WC | (0.007) | ||
| 4 | PA | (0.010) | FBS | (0.012) | DBP | (0.010) | PA | (0.011) | FBS | (0.015) | WC | (0.010) | PA | (0.002) | WT | (0.005) | TG | (0.006) | ||
| 5 | HT | (0.008) | DBP | (0.012) | TG | (0.009) | HT | (0.010) | BMI | (0.013) | FBS | (0.010) | WT | (0.002) | DBP | (0.005) | FBS | (0.005) | ||
| Cancer | Male | 1 | AGE | (0.869) | AGE | (0.855) | AGE | (0.782) | AGE | (0.916) | AGE | (0.895) | AGE | (0.821) | AGE | (0.872) | AGE | (0.847) | AGE | (0.776) |
| 2 | SMK | (0.029) | SMK | (0.026) | AST | (0.028) | SMK | (0.030) | SMK | (0.029) | LDL | (0.029) | SMK | (0.041) | SMK | (0.038) | LDL | (0.041) | ||
| 3 | BMI | (0.029) | DBP | (0.019) | SMK | (0.021) | WT | (0.011) | FBS | (0.013) | AST | (0.026) | WC | (0.022) | FBS | (0.021) | SMK | (0.032) | ||
| 4 | WC | (0.021) | WC | (0.017) | HGB | (0.020) | DRK | (0.011) | SBP | (0.012) | SMK | (0.025) | BMI | (0.021) | BMI | (0.017) | FBS | (0.019) | ||
| 5 | WT | (0.016) | BMI | (0.016) | LDL | (0.020) | WC | (0.011) | DRK | (0.010) | TG | (0.014) | PA | (0.015) | WC | (0.017) | HGB | (0.016) | ||
| Female | 1 | AGE | (0.908) | AGE | (0.882) | AGE | (0.777) | AGE | (0.962) | AGE | (0.954) | AGE | (0.886) | AGE | (0.772) | AGE | (0.711) | AGE | (0.589) | |
| 2 | DRK | (0.025) | FBS | (0.029) | AST | (0.050) | PA | (0.099) | SMK | (0.112) | AST | (0.048) | WC | (0.042) | DBP | (0.048) | LDL | (0.046) | ||
| 3 | WC | (0.016) | DRK | (0.021) | ALT | (0.031) | SMK | (0.018) | FBS | (0.011) | HGB | (0.013) | PA | (0.041) | BMI | (0.040) | TG | (0.045) | ||
| 4 | BMI | (0.015) | SBP | (0.015) | TCHOL | (0.026) | WC | (0.007) | SBP | (0.005) | LDL | (0.013) | BMI | (0.040) | SBP | (0.034) | AST | (0.044) | ||
| 5 | SMK | (0.014) | SMK | (0.011) | HGB | (0.023) | BMI | (0.006) | PA | (0.004) | SMK | (0.012) | HT | (0.039) | WC | (0.030) | DBP | (0.030) | ||
| Hypertension | Male | 1 | AGE | (0.546) | SBP | (0.350) | AGE | (0.286) | AGE | (0.574) | AGE | (0.318) | AGE | (0.277) | AGE | (0.513) | SBP | (0.330) | AGE | (0.304) |
| 2 | BMI | (0.200) | AGE | (0.299) | FBS | (0.270) | BMI | (0.191) | SBP | (0.315) | SBP | (0.215) | BMI | (0.227) | AGE | (0.312) | DBP | (0.222) | ||
| 3 | WC | (0.124) | DBP | (0.165) | SBP | (0.189) | WC | (0.124) | DBP | (0.137) | DBP | (0.163) | WC | (0.139) | DBP | (0.139) | SBP | (0.170) | ||
| 4 | DRK | (0.074) | WC | (0.047) | DBP | (0.056) | DRK | (0.061) | BMI | (0.053) | BMI | (0.068) | DRK | (0.057) | WC | (0.073) | BMI | (0.092) | ||
| 5 | HT | (0.021) | BMI | (0.042) | WC | (0.046) | HT | (0.018) | FBS | (0.047) | FBS | (0.043) | FH_HTN | (0.019) | BMI | (0.066) | WC | (0.053) | ||
| Female | 1 | AGE | (0.709) | SBP | (0.378) | SBP | (0.401) | AGE | (0.711) | SBP | (0.378) | SBP | (0.369) | AGE | (0.484) | SBP | (0.349) | SBP | (0.303) | |
| 2 | BMI | (0.161) | AGE | (0.352) | AGE | (0.345) | BMI | (0.160) | AGE | (0.366) | AGE | (0.355) | BMI | (0.192) | AGE | (0.263) | AGE | (0.229) | ||
| 3 | WC | (0.060) | DBP | (0.121) | DBP | (0.097) | WC | (0.082) | DBP | (0.107) | DBP | (0.103) | WC | (0.095) | BMI | (0.086) | BMI | (0.064) | ||
| 4 | HT | (0.019) | BMI | (0.051) | BMI | (0.048) | FH_HTN | (0.016) | BMI | (0.054) | BMI | (0.049) | PA | (0.070) | WC | (0.059) | DBP | (0.046) | ||
| 5 | FH_HTN | (0.017) | WC | (0.041) | WC | (0.028) | HT | (0.013) | WC | (0.048) | WC | (0.043) | HT | (0.051) | DBP | (0.059) | WC | (0.043) | ||
| Diabetes | Male | 1 | AGE | (0.657) | FBS | (0.468) | FBS | (0.381) | AGE | (0.668) | AGE | (0.409) | AGE | (0.389) | AGE | (0.536) | AGE | (0.320) | AGE | (0.311) |
| 2 | WC | (0.129) | AGE | (0.318) | AGE | (0.307) | WC | (0.129) | FBS | (0.363) | FBS | (0.364) | BMI | (0.185) | FBS | (0.314) | FBS | (0.244) | ||
| 3 | BMI | (0.118) | WC | (0.061) | SBP | (0.054) | BMI | (0.124) | WC | (0.064) | WC | (0.052) | WC | (0.142) | BMI | (0.113) | GGT | (0.086) | ||
| 4 | FH_DM | (0.028) | BMI | (0.050) | WC | (0.042) | FH_DM | (0.022) | BMI | (0.058) | GGT | (0.045) | SMK | (0.036) | WC | (0.079) | WC | (0.063) | ||
| 5 | SMK | (0.027) | SMK | (0.025) | GGT | (0.040) | SMK | (0.020) | SBP | (0.056) | ALT | (0.041) | FH_DM | (0.029) | SMK | (0.033) | SBP | (0.049) | ||
| Female | 1 | AGE | (0.731) | AGE | (0.500) | AGE | (0.461) | AGE | (0.739) | AGE | (0.535) | AGE | (0.494) | AGE | (0.650) | AGE | (0.463) | AGE | (0.404) | |
| 2 | BMI | (0.113) | FBS | (0.232) | FBS | (0.265) | BMI | (0.117) | FBS | (0.200) | FBS | (0.253) | BMI | (0.157) | FBS | (0.160) | FBS | (0.225) | ||
| 3 | WC | (0.095) | HT | (0.102) | GGT | (0.061) | WC | (0.099) | HT | (0.090) | WC | (0.051) | WC | (0.115) | SBP | (0.122) | WC | (0.074) | ||
| 4 | FH_DM | (0.018) | WC | (0.048) | WC | (0.051) | FH_DM | (0.019) | BMI | (0.045) | BMI | (0.044) | FH_DM | (0.022) | WC | (0.087) | BMI | (0.064) | ||
| 5 | HT | (0.012) | BMI | (0.033) | BMI | (0.029) | HT | (0.009) | WC | (0.033) | GGT | (0.042) | PA | (0.015) | BMI | (0.058) | TG | (0.059) | ||
Feature names: AGE: Age; ALT: Alanine aminotransferase; BMI: Body mass index; DBP: Diastolic blood pressure; DRK: Alcohol intake; EGFR: Estimated glomerular filtration rate; FBS: Fasting blood sugar; FH_DM: Family history of diabetes; FH_HTN: Family history of hypertension; GGT: Gamma glutamyl transferase; HGB: Hemoglobin; HT: Height; PA: Physical activity; SBP: Systolic blood pressure; SCR: Creatinine; SMK: Smoking amount; TCHOL: Total cholesterol; TG: Triglycerides; WC: Waist circumference; WT: Weight.