Table 4. Adjusted coefficients examining direct effects of prepubertal risk factors on age at pubic hair onset (TS II); direct effects of prepubertal risk factors and age at pubic hair onset (TS II) on the adulthood CMR composite; and mediated effects of prepubertal risk factors on the adulthood CMR composite via age at pubic hair onset (TS II).

	Prepubertal risk factors, pubertal timing (pubic hair), and adulthood cardiometabolic risk
	Direct Effects: Prepubertal risk factors → pubertal timing (pubic hair TS II)		Direct Effects: Prepubertal risk factors and pubertal timing (pubic hair TS II) → CMR composite		Mediated Effects: Prepubertal risk factors → pubertal timing (pubic hair TS II) → CMR composite
	DV: Pubic Hair TS II		DV: CMR Composite		DV: CMR Composite
	Effect Estimate	95% CI	Effect Estimate	95% CI	Effect Estimate	95% CI
PREDICTORS:
Prepubertal risk factors:
Maternal menarcheal age	0.103****	0.055, 0.151	0.012	-0.061, 0.085	-0.019**	-0.036, -0.005
Black (vs. White)	-0.572****	-0.797, -0.348	-0.027	-0.338, 0.284	0.104**	0.032, 0.194
Latina (vs. White)	-0.096	-0.438, 0.246	-0.156	-0.632, 0.320	-	-
Asian/PI (vs. White)	-0.093	-0.715, 0.528	-0.334	-1.196, 0.528	-	-
Other (vs. White)	0.175	-0.234, 0.584	-0.242	-0.790, 0.306	-	-
General health rating	-0.056	-0.169, 0.057	-0.002	-0.156, 0.152	-	-
BMI percentile	-0.002†	-0.005, 0.0004	0.007***	0.003, 0.010	0.0004†	-0.000, 0.001
Child SES	0.010	-0.079, 0.099	-0.167*	-0.315, -0.019	-	-
Mother-child attachment	0.025	-0.221, 0.271	0.048	-0.330, 0.426	-	-
Maternal sensitivity	-0.035	-0.129, 0.060	-0.126†	-0.274, 0.021	-	-
Negative life events	0.002	-0.101, 0.105	0.020	-0.141, 0.180	-	-
Pubertal timing indictor:
Pubic hair TS II	-	-	-0.182**	-0.303, -0.062	-	-

^†p < .10

*p< .05

**p< .01

***p< .001

****p< .0001.