Table 5. Adjusted coefficients examining direct effects of prepubertal risk factors on menarcheal age; direct effects of prepubertal risk factors and menarcheal age on the adulthood CMR composite; and mediated effects of prepubertal risk factors on the adulthood CMR composite via menarcheal age.

	Prepubertal risk factors, pubertal timing (menarcheal age), and adulthood cardiometabolic risk
	Direct Effects: Prepubertal risk factors → pubertal timing (menarcheal age)		Direct Effects: Prepubertal risk factors and pubertal timing (menarcheal age) → CMR composite		Mediated Effects: Prepubertal risk factors → pubertal timing (menarcheal age) → CMR composite
	DV: Menarcheal Age		DV: CMR Composite		DV: CMR Composite
	Effect Estimate	95% CI	Effect Estimate	95% CI	Effect Estimate	95% CI
PREDICTORS:
Prepubertal risk factors:
Maternal menarcheal age	0.268****	0.208, 0.328	0.032	-0.042, 0.106	-0.039**	-0.067, -0.013
Black (vs. White)	-0.426*	-0.754, -0.098	0.016	-0.289, 0.321	0.062**	0.009, 0.136
Latina (vs. White)	-0.263	-0.668, 0.141	-0.176	-0.655, 0.303	-	-
Asian/PI (vs. White)	-0.745*	-1.412, -0.079	-0.425	-1.277, 0.427	0.108*	0.007, 0.251
Other (vs. White)	-0.061	-0.590, 0.467	-0.282	-0.833, 0.269	-	-
General health rating	-0.040	-0.186, 0.107	0.002	-0.151, 0.156	-	-
BMI percentile	-0.005**	-0.009, -0.001	0.006**	0.002, 0.010	0.001**	0.0001, 0.002
Child SES	0.193**	0.076, 0.310	-0.141†	-0.296, 0.015	-0.028**	-0.057, -0.007
Mother-child attachment	0.010	-0.325, 0.346	0.046	-0.336, 0.428	-	-
Maternal sensitivity	-0.001	-0.126, 0.125	-0.120	-0.269, 0.028	-	-
Negative life events	-0.024	-0.151, 0.103	0.016	-0.143, 0.175	-	-
Pubertal timing indicator:
Menarcheal age	-	-	-0.145**	-0.239, -0.051	-	-

^†p < .10

*p< .05

**p< .01

***p< .001

****p< .0001.