| SC | stem cells |
| MSCs | mesenchymal stem cells |
| Sc-exos | stem cell-derived exosomes |
| EVs | extracellular vesicles |
| CSF | cerebrospinal fluid |
| DM | diabetes mellitus |
| hESCs | human embryonic stem cells |
| iPSCs | induced pluripotent stem cells |
| TGF-ß | transforming growth factor beta |
| VEGF | vascular endothelial growth factor |
| IL | interleukin |
| CCL7 | chemokine ligand 7 |
| CxCL2 | chemokine ligand 2 |
| miRNA, miR | microRNA |
| ncRNA | non-coding RNA |
| ESE | endosomes |
| CME | clathrin-mediated endocytosis |
| ClE | clathrin-independent endocytosis |
| ARF6 | ADP-ribosylation factor 6 |
| CLIC | clathrin-independent carriers |
| GEEC | glycosylphosphatidylinositol-enriched endocytic compartment |
| LSE | late-sorting endosome |
| GDP | guanosine diphosphate |
| ILVS | intraluminal vesicles |
| MVBs | multivesicular bodies |
| ESCRT | endosomal sorting complex required for transport |
| S1P | sphingosine 1 phosphate |
| EGFR | epidermal growth factor receptor |
| mRNA | messenger RNAs |
| CRC | colorectal cancer |
| CEA | carcinoembryonic antigen |
| CA19-9 | cancer antigen 19-9 |
| sEV | small EVs |
| NSCLC | non-small-cell lung cancer |
| NSCLC-sEVs | NSCLC-derived sEVs |
| SCLC | smallcell lung cancer |
| GPI | glycosylphosphatidylinositol |
| PI3K | phosphatidylinositol-3-kinase |
| PLC | phospholipase C |
| ADSCs | Adipose-derived stem cells |
| TEM | Transmission Electron Microscopy |
| ADSC-exos | ADSC-derived exosomes |
| ACER2 | alkaline ceramidase 2 |
| HUVECs | human umbilical vein endothelial cells |
| BMSCs | bone marrow-derived stem cells |
| NTA | nanoparticle tracking analysis |
| BMSC-exos | BMSC-derived exosomes |
| HFMSCs | Hair follicle-derived mesenchymal stem cells |
| HFMSC-exos | HFMSC-derived exosomes |
| TFs | transcription factors |
| LV | left ventricular |
| HDAC1 | histone deacetylase 1 |
| HIF | hypoxia inducible factor |
| NSCs | neural stem cells |
| SVZ | subventricular zone |
| NSC-exos | NSC-derived exosomes |
| OPCs | oligodendrocyte precursor cells |
| PSA | Prostate-Specific Antigen |
| CSCs | Cancer stem cells |
| CSC-exos | CSC-derived exosomes |
| ECSCs | esophageal carcinoma stem cell |
| LCSCs | lung cancer stem cells |
| T1DM | type 1 diabetes mellitus |
| Tregs | regulatory T cells |
| IR | insulin resistance |
| PBMCs | peripheral blood mononuclear cells |
| ET-1 | endothelin 1 |
| DR | diabetic retinopathy |
| PCOS | polycystic ovarian syndrome |
| IBD | inflammatory bowel disease |
| Lgr5 | leucine-rich repeat-containing G protein-coupled receptor 5 |
| ERK | extracellular-signal-regulated kinase |
| Mecp2 | methyl CpG binding protein-2 |
| PDGF | platelet-derived growth factor |
| EPCs | endothelial progenitor cells |
| SIRT1 | sirtuin-1 |
| CXCL12 | CXC chemokine-12 |
| Nrf2 | nuclear factor E2 related factor 2 |
| HCC | hepatocellular carcinoma |
| TRAIL | tumor necrosis factor-related apoptosis-inducing ligand |
| TRIM59 | tripartite motif 5 |
| RHPN2 | rhophilin Rho GTPase binding protein 2 |
| SEM | scanning electron microscopy |
| DLS | dynamic light scattering |
| LC-MS-MS | liquid chromatography with tandem mass spectroscopy |
| 2DGE | two-dimensional gel electrophoresis |
| RT-qPCR | reverse transcriptase quantitative polymerase chain reaction |
| FM | fluorescent microscopy |
| CKD | chronic kidney disease |
| AIS | acute ischemic stroke |
| AF4 | asymmetric flow field flow fractionation |