FIG. 4.

Plasma from an HGV (A)- and HCV (B)-coinfected individual was fractionated by saline flotation density gradients as previously described (8, 10). The top, middle, and bottom fractions were subsequently fractionated on 20 to 60% sucrose gradients. HGV separated into two distinct peaks (A), whereas HCV demonstrated a mixture of particle types (B). The density is shown at the top in grams per milliliter.