Table 4.
Median concentrations of investigated inflammatory markers depending on the stage of cervical cancer.
| Inflammatory Marker | CC Early Stage (I–II Stage) |
CC Advanced-Stage (III–IV Stage) |
p Value |
|---|---|---|---|
| Median [25th–75th Percentile], pg/mL | |||
| TNF-α | 60.7 [40.5–70.4] |
63.4 [55.8–75.9] |
0.215 |
| IFN-β | 97.2 [83.8–115.4] |
95.8 [84.0–102.9] |
0.402 |
| IFN-γ | 1783.05 [1711.5–2512.3] |
1802.4 [1756.3–2550.1] |
0.138 |
| IL-1β | 168.2 [142.5–327.5] |
235.1 [169.3–370.0] |
0.01 |
| IL-2 | 550.5 [134.2–584.0] |
290.1 [115.6–576.4] |
0.072 |
| IL-6 | 23.5 [14.1–44.7] |
37.8 [23.4–102.8] |
0.004 |
| IL-10 | 1140.7 [652.6–1462.0] |
1346.6 [840.0–1470.9] |
0.472 |
| IL-12p70 | 667.8 [151.3–701.4] |
380.5 [151.3–686.4] |
0.108 |
| LCN2 | 12 754.6 [1279.4–32,539.8] |
35,128.3 [26,558.0–40,071.3] |
<0.001 |
| TREM-1 | 339.4 [211.6–397.1] |
391.3 [325.3–472.3] |
0.029 |
p value, Mann–Whitney test; CC—cervical cancer.