Table 2.
Comparison of clinical characteristics between sepsis patients with vitamin C + conventional treatment and sepsis without vitamin C at follow-up.
| Variable | Conventional Treatment n = 18 |
Vitamin C + Conventional Treatment n = 16 |
p |
|---|---|---|---|
| Total antibiotics use, units | 2.17 ± 1.29 | 1.75 ± 0.77 | 0.26 |
| Time of antibiotics use, days | 14.78 ± 9.59 | 10.00 ± 5.03 | 0.08 |
| ICU length of stay, days | 11.44 ± 7.39 | 9.81 ± 5.32 | 0.46 |
| Hospital length of stay, days | 15.33 ± 9.86 | 11.75 ± 5.37 | 0.19 |
| Time of mechanical ventilation, days | 3.89 ± 5.68 | 4.50 ± 5.57 | 0.75 |
| Mechanical ventilation stopped at 5 days | 5 (55.6) | 4 (44.4) | 1.0 |
| Use time of amines, days | 2.89 ± 4.01 | 1.94 ± 3.38 | 0.46 |
| Vasoactive amine reduction at 5 days | 5 (71.4) | 2 (28.6) | 1.0 |
| SOFA * score at 72 h, mid (range) | 11 (6–17) | 11 (7–18) | 0.99 |
| Decrease in SOFA (after 72 h) | 5 (27.8) | 10 (62.5) | 0.04 |
| MAP ** 72 h, units | 78.89 ± 15.66 | 82.63 ± 13.14 | 0.46 |
| Platelets 72 h | 217.56 ± 116.10 | 298.00 ± 115.09 | 0.05 |
| Creatinine 72 h | 1.36 ± 1.60 | 1.11 ± 0.66 | 0.57 |
| 30-day mortality rate, n (%) | 10 (55.6) | 3 (18.8) | 0.03 |
Quantitative variables are expressed as means ± SD, and qualitative variables are expressed in frequencies (%). Comparison of qualitative variables was performed using Chi-square test. Comparisons of quantitative variables were made with Student t-test. Statistical significance was considered at p ≤ 0.05 level. * SOFA: sequential organ failure assessment; ** MAP: mean arterial pressure.