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. 2024 Mar 12;60(3):464. doi: 10.3390/medicina60030464

Table 2.

Comparison of clinical characteristics between sepsis patients with vitamin C + conventional treatment and sepsis without vitamin C at follow-up.

Variable Conventional Treatment
n = 18
Vitamin C + Conventional Treatment
n = 16
p
Total antibiotics use, units 2.17 ± 1.29 1.75 ± 0.77 0.26
Time of antibiotics use, days 14.78 ± 9.59 10.00 ± 5.03 0.08
ICU length of stay, days 11.44 ± 7.39 9.81 ± 5.32 0.46
Hospital length of stay, days 15.33 ± 9.86 11.75 ± 5.37 0.19
Time of mechanical ventilation, days 3.89 ± 5.68 4.50 ± 5.57 0.75
Mechanical ventilation stopped at 5 days 5 (55.6) 4 (44.4) 1.0
Use time of amines, days 2.89 ± 4.01 1.94 ± 3.38 0.46
Vasoactive amine reduction at 5 days 5 (71.4) 2 (28.6) 1.0
SOFA * score at 72 h, mid (range) 11 (6–17) 11 (7–18) 0.99
Decrease in SOFA (after 72 h) 5 (27.8) 10 (62.5) 0.04
MAP ** 72 h, units 78.89 ± 15.66 82.63 ± 13.14 0.46
Platelets 72 h 217.56 ± 116.10 298.00 ± 115.09 0.05
Creatinine 72 h 1.36 ± 1.60 1.11 ± 0.66 0.57
30-day mortality rate, n (%) 10 (55.6) 3 (18.8) 0.03

Quantitative variables are expressed as means ± SD, and qualitative variables are expressed in frequencies (%). Comparison of qualitative variables was performed using Chi-square test. Comparisons of quantitative variables were made with Student t-test. Statistical significance was considered at p ≤ 0.05 level. * SOFA: sequential organ failure assessment; ** MAP: mean arterial pressure.