Table 1.
Baseline characteristics of all the study participants and stratified according to the SUA/sCr ratio threshold predictive for cardiovascular mortality.
| Variables | Total Sample | SUA/sCr Ratio | |
|---|---|---|---|
| ≤5.35 | >5.35 | ||
| No. of participants | 2230 | 1038 | 1192 |
| Age (years) | 65.0 (12.7) | 64.6 (12.9) | 65.3 (12.6) |
| Gender (M/F%) | 51.2/48.8 | 52.3/47.7 | 50.2/49.8 |
| Cigarette Smoking (%) | 18.3 | 20.0 | 16.8 * |
| BMI (kg/m2) | 28.5 (4.6) | 27.8 (4.5) | 29.1 (4.6) * |
| Normal-weight (%) | 21.4 | 26.4 | 17.0 |
| Overweight (%) | 45.7 | 45.5 | 46.0 |
| Obesity (%) | 32.9 | 28.1 | 37.0 * |
| Systolic BP (mmHg) | 151.5 (26.1) | 150.6 (26.0) | 152.3 (26.1) |
| Diastolic BP (mmHg) | 85.3 (12.5) | 85.1 (12.4) | 85.5 (12.6) |
| Hypertension (%) | 76.2 | 74.3 | 77.9 * |
| Creatinine (mg/dL) a | 0.93 (1.3) | 1.01 (1.3) | 0.88 (1.2) * |
| eGFR (mL/min/1.73 m2) a | 72.4 (1.4) | 66.1 (1.4) | 77.6 (1.3) * |
| Kidney dysfunction-eGFR ≤ 60 mL/min/1.73 m2 (%) | 23.9 | 32.4 | 16.5 * |
| Serum Uric Acid (mg/dL) a | 5.01 (1.3) | 4.2 (1.3) | 5.9 (1.2) * |
| Glucose (mg/dL) a,b | 134.9 (1.4) | 138.0 (1.4) | 131.8 (1.3) |
| Total cholesterol (mg/dL) a,c | 208.9 (1.2) | 204.2 (1.2) | 208.9 (1.2) |
| Triglycerides (mg/dL) a,c | 134.9 (1.7) | 131.8 (1.7) | 141.2 (1.7) * |
| HDL-cholesterol (mg/dL) a,d | 46.8 (1.3) | 46.8 (1.3) | 46.9 (1.2) |
| Triglycerides (mg/dL)/HDL-cholesterol (mg/dL) d | 3. 7 (3.1) | 3.5 (2.9) | 3.8 (3.3) |
| Statin use (%) | 6.7 | 5.6 | 7.7 |
Data are expressed as means (SD); BMI: body mass index; BP: Blood Pressure; eGFR: estimated glomerular filtration rate. Overweight was defined as a BMI between 25 and 29.9 kg/m2 and obesity as BMI ≥ 30 kg/m2. Hypertension was defined as office systolic BP ≥ 140 and/or diastolic BP ≥ 90 mmHg or current antihypertensive drug treatment. a Data are expressed as geometric mean (SD); b sample reduced by 15%; c sample reduced by 5%; d sample reduced by 20%; * >5.35 vs. ≤5.35: p < 0.05.