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. 2024 Feb 21;12(3):440. doi: 10.3390/microorganisms12030440

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© 2024 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Volcano plot of differentially regulated baseline plasma circulating microRNAs in patients hospitalized with acute SARS-CoV-2 infection. Differential miRNA levels were determined by comparing plasma miRNA expression profiles between SARS-CoV-2-infected patients and the uninfected healthy control group. To identify biomarker candidates, cutoffs of effect size (fold change [FC] >1.2) and significance level (adjusted p [padj] < 0.05) were used. A set of 190 differentially expressed (DE) (red) miRNAs was identified.