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. Author manuscript; available in PMC: 2024 Mar 27.
Published in final edited form as: World J Biol Psychiatry. 2022 Oct 6;24(5):333–386. doi: 10.1080/15622975.2022.2112074
Statement: A combination of work focused counselling and work-directed interventions could be used to reduce depressive symptoms in people with Major Depressive Disorder
Recommendation Grade: 2
Strength of evidence: Limited; Grade B
Acceptability: Good
Clinical recommendation was based on: 1x Cochrane review (N= 8 trials, 1091 participants)(Nieuwenhuijsen et al. 2020)
Reported effect size: Small (Standard mean difference=0.25)(Nieuwenhuijsen et al. 2020)
Risk of Bias assessment: Low ROB meta-analysis of high ROB individual trials.